(Sports Network) - Through his first two starts as a St. Ravens Rice Jersey. Louis Cardinal, Brad Penny has resembled the pitcher who made two straight All-Star teams earlier in his career. Hes usually looked like a frontline starter when facing the Arizona Diamondbacks, however. Penny will be attempting to extend his career success against the slumping Diamondbacks when the Cardinals head to Chase Field this evening for the opener of a three-game series. A 16-game winner for the Los Angeles Dodgers in 2006 and 2007, Penny struggled with ineffectiveness and injuries while pitching for three different teams over the past two years. He seems to have found a comfort zone in St. Louis, though, after signing a one-year deal with the defending National League Central champions in December. Penny held Cincinnati to one run in a seven-inning no-decision in his first start of the year, then followed up with another seven-inning gem in Wednesdays 2-1 victory over Houston. The bulky right-hander yielded only one unearned run and three hits and did not issue a walk in picking up the win. Hes traditionally been tough for the Diamondbacks to handle, owning a 9-3 record with a stellar 1.96 earned run average over 17 career starts against tonights opponent. Penny tossed a complete-game six-hitter versus Arizona in his final outing of 2009, leading the San Francisco Giants to a 4-1 decision on September 30. Penny will be taking on an Arizona squad mired in a four-game losing streak and which mustered only six runs over three defeats in San Diego over the weekend. The Diamondbacks were in position to end their skid in Sundays finale, but the Padres rallied for five runs in the bottom of the seventh inning to pull out a 5-3 win. Arizona carried a 2-0 lead into the bottom of the seventh that relievers Aaron Heilman and Juan Gutierrez failed to protect. Heilman surrendered three runs on three hits while recording just two outs to take the loss, while Gutierrez allowed a two-run double to Chase Headley that snapped a 2-2 tie. I made some good pitches, and I made some bad pitches, Heilman said. It was one of those days. I cant put my finger on it. Ian Kennedy shut the Padres out over the first five innings, striking out seven and giving up only two hits. Mark Reynolds led Arizona offensively by going 3-for-4 with two RBI and smashing his fourth home run of the season. The Cardinals, on the other hand, come in off a comeback win their last time out, overcoming an early three-run deficit in a 5-3 triumph over the New York Mets last night. Ryan Ludwick put St. Louis ahead to stay with a tie-breaking two-run homer in the bottom of the eighth inning. Ludwick finished 2-for-2 with three walks for the Cardinals, who also received a game-tying three-run homer from Colby Rasmus in the fifth inning and a 3- for-3 effort at the plate out of Matt Holliday. It felt good. I was beginning to wonder if I could even hit a home run anymore, said Ludwick after belting his first long ball of the season. It felt nice, especially in that moment and that scenario. Adam Wainwright made a big contribution as well for St. Louis, with the standout hurler going the distance on a four-hitter while striking out nine batters to move to 3-0 on the young season. It was a much-needed complete game, with the St. Louis bullpen taxed after Saturdays 20-inning loss to the Mets. The Cardinals will be taking their swings tonight off Rodrigo Lopez in the offseason additions third start as a member of the Diamondbacks. Lopez was outstanding in his season debut, firing six innings of one-run ball to defeat Pittsburgh at Chase Field on April 9, but was hit hard at Los Angeles this past Wednesday. The journeyman righty permitted five runs (4 earned) on 11 hits through five innings and did not receive a decision in Arizonas 9-7 win. The 34-year-old signed with the Diamondbacks as a non-roster invitee over the winter and earned a spot in the teams rotation with a strong spring. Lopez spent most of 2009 in the Philadelphia Phillies organization and went 3-1 with a 5.70 ERA over seven appearances (5 starts) in the majors before being released in September. One of Lopezs wins last year came against the Cardinals, a 14-6 verdict back in July in which the native Mexican allowed four runs (3 earned) on 10 hits over six frames. Hes 2-1 in three career meetings with St. Louis, but has a 6.35 ERA over those games. 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